Is it time to do it?
From AlleleBlog: http://blog.allelebiotech.com/2012/08/cord-banking-and-ips-cells/
Umbilical Cord Banking (UCB) has been a popular discussion topic in
the United States since the first Cord Bank was established in New York
in 1992. Since the first cord blood transplantation in 1988, there have
been over 780,000 UCB donations to private banks and 400,000 UCB
donations to public blood banks worldwide. There has been such a great
number of donations because UCB is full of hematopoietic progenitor
cells, which makes it a more desirable solution to genetic, metabolic
and immune disorders, over bone marrow and blood. Because of the nature
of UCB, the recipient does not need to be an immunological match, there
is a lower rate of infection and it is much easier to acquire than bone
marrow, making it the ideal form of treatment for many patients and
practitioners.
Over twenty years later, a new technology is emerging that could
provide some clarity to the “to donate or not to donate” debate: induced
pluripotent stem cells (iPSC). Derived from adult cells, iPSCs have
the potential to be used like UCB or reprogrammed into specific tissue
like myocytes. This potential opens up banking to countless individuals
born before 1992, who never had an option to bank their UCB. With this
unbounded potential, should iPSCs be banked liked UCB? Supporters argue
that there has been enough evidence thus far to start a bank, however,
most people seem to agree that too much is unknown about iPSCs and their
use in humans. With that, most are in agreement that iPSC research is
absolutely needed so banking can become a reality in the future.
For now iPSCs will remain in the testing and research phase, however,
based on current research, iPSCs have the potential to enhance Cord
Blood that has already been banked, perhaps providing some relief to
public banks in the future (Broxmeyer, 2010). Though the potential of
iPSCs is endless, more work has to be done before they are placed in
humans and considered a viable banking system.
Tuesday, August 7, 2012
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